Cardiovascular Research oct2018

Latest publication (October 2018)

Åsmund T Røe Marianne Ruud Emil K Espe Ornella Manfra Stefano Longobardi Jan M Aronsen Einar Sjaastad Nordén Trygve Husebye Terje R S Kolstad Alessandro Cataliotti Geir Christensen Ole M Sejersted Steven A Niederer Geir Øystein Andersen Ivar Sjaastad William E Louch

Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression

Read the article in Cardiovascular Research


Prize winners of the Poster Session, CHFR 2018

Presentations from our Institute which got the first prize during the 16th Annual CHFR Symposium:

Kate Herum winner of Session II: "Syndecan-4 shedding exposes OPN to cleavage by thrombin thereby promoting fibrosis in late phase cardiac remodeling following pressure overload",
was represented by second author Andreas Romaine.

Emil Espe winner of Session V, presented: "A noninvasive index of regional myocardial power using MRI"

Other poster presentations from our Institute ranked top 3 in their sessions, were presented by Sabrina Mathiesen, Arne Olav Melleby, Yufeng Hou and Henriette Andresen and Mari Elen Strand.


Click to see pictures from:
- The Annual CHFR Symposium 2018

- The Cardiac Café

- The Moderated poster sessions


Latest publication (September 2018)

Andenæs,K.; Lunde,I.G.; Mohammadzadeh,N.; Dahl,C.P.; Aronsen,J.M.; Strand,M.E.; Palmero,S.; Sjaastad,I.; Christensen,G.; Engebretsen,K.V.T.; Tønnessen,T.

The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling



Latest publication (August 2018)

Raffaele Altara,Rana Ghali,Ziad Mallat, Alessandro Cataliotti,George W Booz,Fouad A Zouein

Conflicting vascular and metabolic impact of the IL-33/sST2 axis

Read the article in Cardiovascular Research

doi: 10.1093/cvr/cvy166


Latest publication (July 2018)

Barth,Z.; Schwartz,T.; Flatø,B.; Aaløkken,T.M.; Koller,A.; Lund,M.B.; Sjaastad,I.; Sanner,H.

The association between nailfold capillary density and pulmonary and cardiac involvement in medium- to long-standing juvenile dermatomyositis

Read the article in Athritis Care Research

Cardiovascular Research

Latest publication (June 2018)

Melleby,A.O.; Romaine,A.; Magnus,Aronsen J.; Veras,I.; Zhang,L.; Sjaastad,I.; Lunde,I.G. & Christensen,G.

A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice

Cardiovascular Research
doi: 10.1093/cvr/cvy141. [Epub ahead of print]

Read the article in Cardiovascular Research


K. G. Jebsen Centre for Cardiac Research at University of Oslo

K.G. Jebsen Centre for Cardiac Research is directed by Professor Ivar Sjaastad: "Our primary objective is to better understand the mechanisms of heart failure. Specifically, we will identify mechanisms regulating myocardial stiffness, and new therapeutic targets of diastolic dysfunction."

The centre comprises six research groups at University of Oslo; of which three are located at Ullevål Hospital, two at Rikshospitalet and one at Radiumhospitalet.

Group leaders: Ivar Sjaastad (Centre leader), Geir Christensen, (Deputy leader), William E. Louch, Camilla Raiborg, Thor Edvardsen and Lars Gullestad
Associated partners: Alessandro Cataliotti, Llewelyn Roderick (University of Cambridge), Joakim Sundnes (Simula) and Kjetil Taskén
Administrative coordinator: Emil Espe

Read more about the K.G. Jebsen Centre for Cardiac Research

Institute for Experimental Medical Research (IEMR)

Institutt for eksperimentell medisinsk forskning (IEMF)
Acting Institute leader: Professor Ivar Sjaastad

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Institute for Experimental
Medical Research (IEMR)

use cutting edge technologies to better understand the mechanisms of heart failure.

Our method competency is comprehensive, and streches from clinical studies to investigation of individual biomolecules.

Excellent science reveals the secrets of the failing heart

Find novel targets for the treatment of heart failure patients.
Develop and employ cutting edge technologies to understand the mechanisms of heart failure.
Recruit and educate PhD and medical students to become tomorrow’s scientific experts.

Webmaster Vidar, IEMF